The A6 is equipped with the latest-generation in active safety features to help the driver maintain control and avoid a crash. Its electronic stability program virtually eliminates skidding of the front or rear tires. Slam on the brakes and the anti-lcok brake system (ABS) allows the driver to maintain steering control by eliminating tire lockup. Electronic Brake-force Distribution transfers braking force to the tires with the best grip to improve braking performance. Brake Assist provides full braking force when it senses the driver has mistakenly reduced pressure on the brake pedal. A tire-pressure monitor alerts the driver to a soft tire.

In the event of a crash, the A6 offers a carefully designed structure, excellent seatbelts, two-stage frontal airbags, side-impact airbags to protect the torso, head airbags to protect the head in a side impact, and active front head airbags to help protect occupants from a collision from behind.