The new cab allows about four inches additional room from side to side for a roomier front seat and a rear seat in the Crew Cab that more easily accommodates three adults across. Front and rear seats are chair height which, for the driver, allows excellent visibility over the hood and improves leg room for rear seat passengers. The front seats are still the first-class section of the cabin, but those in coach won't have to endure the pain of the old sideways-mounted seats in extended cabs. The Canyon's extended cab is large enough to orient its occasional passengers facing forward.

The instrument panel has large white numerals on a black background with the orange needles that GM loves. Lighting functions are clustered on the dash to the left of the steering wheel; there are no switches in any remote location.

Similarly, the center stack, on a raised portion of the stack on silver-colored plastic, groups the 4x4 functions, the audio and the HVAC functions each with their own. The emergency flasher button is high on the dash where it's easily seen. The cruise control function, however, is the same turn signal stalk system GM has had for decades, albeit refined. Some people hate it; others are don't mind it and are familiar with it.

The Canyon features triple seals around the doors, an example of refinement over the old Sonoma. These not only reduce water and dust intrusion, they also reduce wind noise for a quieter cab.